Description

B-cell receptor CD22 (CD22). Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. It seems to be involved in regulation of B-cell antigen receptor signaling.


Clinical trials

NCT04556669 - Cervical Cancer
NCT03638206 - Colorectal Cancer, Esophagus Cancer, Renal Carcinoma, Hepatoma, Lung Cancer, Mesothelioma, Ovarian Cancer, Pancreatic Cancer, Melanoma
NCT04556669 - Sarcoma


Target gene expression

The following plot describes the expression, in different tissues and TCGA cancers, of the different isoforms of the gene CD22.


Target essentiality


Protein properties

The following plot describes the target topology, highlighting the position of the endo-, ecto- and transmembrane domains, as well as the position of a signal peptide, when present. The last three rows describe the position of potential epitopes, as well as phosphorylation and glycosylation sites.